120287-85-6

  • Product Name:Cetrorelix Acetate
  • Molecular Formula:C70H92ClN17O14
  • Purity:99%
  • Molecular Weight:1431.06
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Product Details;

CasNo: 120287-85-6

Molecular Formula: C70H92ClN17O14

Appearance: White powder

Manufacturer supply high quality Cetrorelix Acetate 120287-85-6 with GMP standards We provide high quality Cetrorelix acetate (CAS 120287-85-6), at a very affordable prices to our customers.

1.What is the Cetrorelix acetate ?

This medication is used by women having certain fertility treatments (controlled ovarian stimulation). Cetrorelix is usually used in combination with other hormones (FSH and hCG).

Cetrorelix was launched in Germany for the treatment of female infertility. It is a decapeptidic analog of luteinizing hormone-releasing hormone (LH-RH) bearing structural modifications in the crucial positions 1, 2, 3, 6 and 10 : [Ac-D-Nal1, D-4-CI Phe-2, D-Pal3, D-Cit6, D-Alal0]-GnRH. Cetrorelix is an extremely potent and long acting gonadotrophin releasing hormone (GnRH) antagonist and thus blocks gonadotrophins and sex steroid secretion immediately after administration. Moreover, it has a low histamine-releasing potency. Cetrorelix will be the first LH-RH antagonist approved worldwide. In several Phase III clinical trials, female patients receiving Cetrorelix had a successful controlled ovulation thus avoiding a premature LH-surge. Cetrorelix could be a first-choice in-vitro fertilization (IVF) treatment without the complications of current controlled ovarian hyperstimulation protocols. Cetrorelix is currently under clinical investigation for the treatment of diverse sex hormone dependent disorders such as benign prostate hypertrophy, breast, ovarian or prostate cancers and diverse gynaecological disorders.

Cetrorelix Acetate is an gonadotropin-releasing hormone antagonist and is used to treat hormone-sensitive cancers of the prostate and breast.

2.What is the CAS number for Cetrorelix acetate ?

The CAS number of Cetrorelix acetate is 120287-85-6.

More information of Cetrorelix acetate 120287-85-6 are:

CAS Number

120287-85-6

Density

1.42 g/cm3

Refractive Index

1.667

PSA

495.67000

LogP

5.93230

Pka

9.82±0.15(Predicted)

3.What is the molecular formula of Cetrorelix acetate ?

The chemical formula of Cetrorelix acetate is C70H92ClN17O14 which containing 70 Carbon atoms,92 Hydrogen atoms,1 Chlorine atoms,17 Nitrogen atoms and 14 Oxygen atoms,and the molecular weight, and the molecular weight of Cetrorelix acetate is 1431.06

4.What is Cetrorelix acetate(120287-85-6)used for?

Cetrorelix was launched in Germany for the treatment of female infertility. It is a decapeptidic analog of luteinizing hormone-releasing hormone (LH-RH) bearing structural modifications in the crucial positions 1, 2, 3, 6 and 10 : [Ac-D-Nal1, D-4-CI Phe-2, D-Pal3, D-Cit6, D-Alal0]-GnRH. Cetrorelix is an extremely potent and long acting gonadotrophin releasing hormone (GnRH) antagonist and thus blocks gonadotrophins and sex steroid secretion immediately after administration. Moreover, it has a low histamine-releasing potency. Cetrorelix will be the first LH-RH antagonist approved worldwide. In several Phase III clinical trials, female patients receiving Cetrorelix had a successful controlled ovulation thus avoiding a premature LH-surge. Cetrorelix could be a first-choice in-vitro fertilization (IVF) treatment without the complications of current controlled ovarian hyperstimulation protocols. Cetrorelix is currently under clinical investigation for the treatment of diverse sex hormone dependent disorders such as benign prostate hypertrophy, breast, ovarian or prostate cancers and diverse gynaecological disorders.

InChI:InChI=1/C70H92ClN17O14/c1-39(2)31-52(61(94)82-51(15-9-28-77-69(73)74)68(101)88-30-10-16-58(88)67(100)79-40(3)59(72)92)83-60(93)50(14-8-29-78-70(75)102)81-63(96)54(34-43-20-25-49(91)26-21-43)86-66(99)57(38-89)87-65(98)56(36-45-11-7-27-76-37-45)85-64(97)55(33-42-18-23-48(71)24-19-42)84-62(95)53(80-41(4)90)35-44-17-22-46-12-5-6-13-47(46)32-44/h5-7,11-13,17-27,32,37,39-40,50-58,89,91H,8-10,14-16,28-31,33-36,38H2,1-4H3,(H2,72,92)(H,79,100)(H,80,90)(H,81,96)(H,82,94)(H,83,93)(H,84,95)(H,85,97)(H,86,99)(H,87,98)(H4,73,74,77)(H3,75,78,102)/t40-,50-,51+,52+,53-,54-,55+,56-,57-,58?/m1/s1

Relevant articles related to Cetrorelix acetate:

Article

Source

The effect of NMeTyr5 substitution in luteinizing hormone-releasing hormone antagonists.

Haviv,Fitzpatrick,Nichols,Swenson,Mort,Bush,Diaz,Nguyen,Holst,Cybulski,et al.

, p. 928 - 933 (1993)

5.Manufacturer supply high quality Cetrorelix Acetate 120287-85-6 with GMP standards

Harbin Jixianglong Biotech Co., Ltd. is a quality supplier of Cetrorelix acetate. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Cetrorelix acetate 120287-85-6.

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